Featured
Allergy Research Group Acquires Metabolic Maintenance
We're excited to announce the acquisition of Metabolic Maintenance, a respected provider of premium supplements known for its commitment to science-based formulations. This strategic acquisition further solidifies ARG’s position in the market and significantly enhances its portfolio, particularly in the burgeoning stress and mood management categories.
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The Role of Cortisol in Dampening Thyroid Function and Flattening Mood
Cortisol level do not merely respond to thyroid dysfunction. It feeds back into the system. Elevated cortisol can suppress thyroid signaling at multiple levels of the HPT axis, further reducing metabolic output. Over time, this creates a reinforcing loop. Lower thyroid hormone availability raises cortisol. Sustained cortisol elevation further dampens thyroid signaling, which leads to emotional flattening, decreased motivation, muted pleasure, slowed thinking, and a more narrow emotional range.
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Holy Basil and Stress Resilience: Clinical Evidence for Supporting Cortisol, Sleep, and Recovery*
Traditional use of holy basil does not utilize it as a stimulant or sedative.* Instead, it is viewed as a botanical that helps the body maintain balance amid physical, emotional, and environmental stressors.* [1] Recent research now offers clearer insight into how it may support stress resilience, cortisol dynamics, and the conditions that allow restorative sleep to emerge.* [1][2]
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Case Report: Viral-Induced Thyroid Dysfunction
At first glance, symptoms like fatigue, body aches, and low-grade fevers feel familiar, but the story quickly becomes more intriguing when the thyroid gets pulled into the plot. This case report walks through the diagnosis pathway of a patient initially believed to be experiencing a common cold, but upon further examination, had actually developed subacute thyroiditis.
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Hypothyroidism and Depression: Why They’re So Often Confused
The overlap between hypothyroidism and depression is not a coincidence. It reflects shared physiology, shared neuroendocrine pathways, and a long history of clinical observation that continues to be supported by modern research. Understanding this overlap requires moving beyond symptom checklists and into the biology of how thyroid hormones interact with the brain.
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Pantothenic Acid (Vitamin B5), Energy Metabolism, and Adrenal Stress Adaptation*
Stress is not simply a hormonal signal, it is an energetically demanding physiological state. The ability to respond to stress, sustain output, and return toward baseline depends on whether cells, particularly those within the adrenal glands, have sufficient metabolic capacity to meet the demands placed upon them. Pantothenic acid can be implemented as a foundational nutrient that supports the body’s ability to meet demand and recover afterward, rather than as a quick fix or hormonal modifier.*
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When Cortisol Loses Its Rhythm: Burnout, Fatigue, and the Case for Adrenal Resilience
Cortisol is not meant to be constant. Under healthy conditions, it follows a daily rhythm that supports alertness and energy availability earlier in the day, then gradually declines to allow for rest and repair. This rhythm reflects an intact feedback system within the HPA axis, enabling cortisol to rise when stress requires it and fall when the demand passes. [1]
Cortisol dysregulation reflects changes in central signaling, feedback sensitivity, hormone availability, and tissue responsiveness, and not a simple excess or deficiency. Treating cortisol as a number to correct risks pushing the system further from balance rather than restoring adaptive range.
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