High-potency bioavailable methylcobalamin to support nerve health, cognitive function, and methylation balance.*
What It Does
B12 Methylcobalamin 3,000 mcg with Folate supports neurological health, red blood cell formation, and cellular energy by delivering a bioavailable, high-dose form of vitamin B12.* It promotes methylation, emotional well-being, and homocysteine regulation in lozenge form supported by 400 mcg of methylfolate and vitamin C.*
How It Works
• Methylcobalamin (Vitamin B12): The active, methylated form of B12 used in the central nervous system and involved in myelin sheath formation, neurotransmitter production, and cellular metabolism.*[1,4,8]
• Methylfolate: Works alongside B12 to support methylation, red blood cell production, and homocysteine metabolism.*[1]
• Homocysteine Balance: B12 facilitates the conversion of homocysteine to methionine, contributing to cardiovascular and cognitive health.*[6]
• Nerve Protection: Methylcobalamin supports myelin synthesis, essential for normal nerve signal transmission and neurological function.*[4,9]
• Mood and Cognition: B12 plays a role in the synthesis of neurotransmitters related to emotional regulation and mental clarity; insufficient levels may impact mood and cognition.*[3,8,10]
• Oral Absorption: Systematic reviews show oral doses of 1,000 mcg or more are effective compared to alternative administration.*[11]
• Low Toxicity: No tolerable upper intake level (UL) is established for B12 due to its safety profile and water-solubility, allowing the body to excrete excess amounts efficiently.*[12]
Who It’s For
This product is ideal for individuals with increased B12 needs due to dietary restrictions, aging, vitamin B-12 depleting medication use, or those seeking to support mood, cognition, and neurological function with a clinically supported dose.*
Special Features
Delivers 3,000 mcg of methylcobalamin per lozenge for reliable, high-potency support in a bioavailable format. Combined with folate to engage methylation and optimize homocysteine metabolism.*
B12 Methylcobalamin 3,000 mcg with Folate offers research-backed, high-dose neurological and metabolic support in one convenient daily lozenge.*
References
1. Baltrusch S. Biomed Res Int. 2021;2021:9968228. doi:10.1155/2021/9968228
2. Pawlak R, et al. Eur J Clin Nutr. 2014;68(5):541–8.
3. Lachner C, et al. J Neuropsychiatry Clin Neurosci. 2012;24(1):5–15.
4. Mumtaz H, et al. Ann Med Surg (Lond). 2022;82:104762. doi:10.1016/j.amsu.2022.104762
5. Infante M, et al. World J Diabetes. 2021;12(7):916–31.
6. Ueno A, et al. Nutrients. 2022;14(7):1494. doi:10.3390/nu14071494
7. Sangle P, et al. Cureus. 2020;12(10):e11169. doi:10.7759/cureus.11169
8. Syed EU, et al. Open Neurol J. 2013;7:44–8.
9. Calderon-Ospina CA, Nava-Mesa MO. CNS Neurosci Ther. 2020;26(1):5–13.
10. Beaudry-Richard A, et al. Ann Neurol. 2025. doi:10.1002/ana.27200
11. Wang H, et al. Cochrane Database Syst Rev. 2018;3(3):CD004655
12. Institute of Medicine. Dietary Reference Intakes. National Academies Press. 1998.
