Allergy Research Group Thyroid Zen Defense - 120 vegetarian capsules bottle front label

Thyroid Zen Defense supplement facts and allergen-free icon graphic showing selenium, myo-inositol, holy basil, and shiitake

Thyroid Zen Defense ingredient or benefits graphic for thyroid, stress, and immune support

SKU 77555

Thyroid Zen Defense

Name: Thyroid Zen Defense
Brand: Allergy Research Group
SKU: 77555
Price: 44.00 USD
Availability: InStock

Supports a Balanced Mood, Thyroid, and Immune Function*

Thyroid Zen Defense is designed to support three key pathways for maintaining healthy thyroid and immune function.* This advanced formula features Holixer® Holy basil extract, clinically studied for its ability to promote cortisol balance and a healthy stress response, both of which are vital for maintaining thyroid health.* A combination of selenium and myo-inositol, included in a clinically-supported ratio, work together to promote thyroid hormone production, cellular function, and overall endocrine balance.* Time-honored shiitake mushroom extract is included to enhance immune resilience and help maintain healthy immune function by supporting natural killer (NK) cell activity and immunomodulation. With its blend of clinically supported and traditional ingredients, Thyroid Zen Defense offers a multi-mechanistic approach to maintaining optimal thyroid, mood, and immune health.

$44.00

Tax excluded.

Quantity:

Ingredients

Serving Size: 2 capsules
Servings Per Container: 60

Amount per serving:

Selenium (as L-selenomethionine): 83 mcg
Myo-Inositol: 600 mg
Holy Basil Extract (as Holixer™ Ocimum sanctum leaf extract, standardized to > 5% Ocimum Bioactive Complex): 125 mg
Shiitake Extract 4:1 (Lentinula edodes, fruiting body): 500 mg

Other Ingredients

Hydroxypropyl methylcellulose, microcrystalline cellulose, magnesium stearate, silicon dioxide.

Suggested Use

As a dietary supplement, take 2 capsules twice daily, or as directed by a healthcare practitioner.

If you are pregnant or lactating, have any health conditions or are taking any medication, consult your healthcare practitioner before use.
Store in a cool, dry place, tightly capped, away from light. Keep out of the reach of children. Use only if safety seal is intact. Variations in product color may occur.

Thyroid Zen Defense

$44.00

What It Does

This formula delivers clinically studied nutrients and botanicals that support thyroid function, stress resilience, and immune system balance.* It targets the intersection of the hypothalamic-pituitary-thyroid (HPT) axis and stress physiology to promote healthy hormone synthesis, immune surveillance, and adaptive responses.*

How It Works

• Holy Basil (Holixer® extract): Clinically shown to reduce perceived stress and support cortisol balance, this adaptogen helps buffer stress-related disruptions to the HPT axis.*[1]
• Myo-Inositol + Selenium: In combination, this duo has been shown in multiple trials to support thyroid hormone biosynthesis and regulation more effectively than selenium alone.*[2–5]
• Myo-Inositol: Supports iodine uptake and organification, essential for thyroid hormone production in thyrocytes.*[4]
• Selenium: A cofactor for deiodinase and antioxidant enzymes (glutathione peroxidases, thioredoxin reductases), selenium protects thyroid tissue from oxidative stress and modulates immune signaling.*[5–7]
• Shiitake Mushroom (Lentinula edodes): Provides immunomodulatory beta-glucans and polysaccharides that influence natural killer (NK) cell activity, supporting immune surveillance and thyroid-immune interaction.*[8,9]
• Immune-Thyroid Interactions: NK cell activity plays a regulatory role in thyroid function, particularly during aging and times of immune activation.*[10]

Who It's For

Designed for individuals seeking stress resilience and thyroid balance, particularly those seeking optimal thyroid health, stress response balance, or immune-thyroid axis support.*

Special Features

Provides a cohesive formula aimed at the triad of stress, thyroid, and immune health.*

References

1. Lopresti AL, et al. Front Nutr. 2022;9:965130. doi:10.3389/fnut.2022.965130
2. Ferrari SM, et al. Eur Rev Med Pharmacol Sci. 2017;21(2 Suppl):36–42.
3. Pace C, et al. Endocr J. 2020;67(11):1093–1098.
4. Paparo SR, et al. Front Endocrinol (Lausanne). 2022;13:930756. doi:10.3389/fendo.2022.930756
5. Nordio M, Basciani S. Eur Rev Med Pharmacol Sci. 2017;21(2 Suppl):51–59.
6. Wang F, et al. Front Endocrinol (Lausanne). 2023;14:1133000. doi:10.3389/fendo.2023.1133000
7. Pirola I, et al. Endocrinol Diabetes Nutr (Engl Ed). 2020;67(1):28–35.
8. Bisen PS, et al. Curr Med Chem. 2010;17(22):2419–2430.
9. Roszczyk A, et al. Int J Mol Sci. 2022;23(16):8980. doi:10.3390/ijms23168980
10. Lee EK, Sunwoo JB. Endocrinol Metab (Seoul). 2019;34(2):132–137

Additional Information

Targeted Thyroid and Stress Response Support with Adaptogens and Immune-Modulating Nutrients*

Thyroid Zen Defense

Supports a Balanced Mood, Thyroid, and Immune Function*

What It Does

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