Herxheimer Support*

• Sodium and Potassium Bicarbonate: Bicarbonate salts provide gentle buffering support, helping maintain normal acid–base balance during periods of increased metabolic demand.* Sodium and potassium provide essential electrolytes involved in fluid balance, nerve signaling, and muscle function.*

• Meriva® Turmeric Phytosome: Science-backed Meriva® provides a patented curcumin-phosphatidylcholine phytosome with enhanced bioavailability.* Clinical studies have shown approximately 29-fold greater total curcuminoid absorption compared with a standard extract.[1] Curcumin supports cytokine balance, antioxidant defenses, and cellular resilience during temporary oxidative stress.*

• Curcuminoids for Recovery Support*: Clinical research on Meriva® has demonstrated support for musculoskeletal comfort, exercise recovery, and physical function, making it a useful botanical option when the body is working through periods of increased immune and oxidative demand.*[2,3]

• Indian Frankincense Gum Extract: Boswellia serrata provides boswellic acids, traditionally used to support joint comfort, mobility, and balanced cytokine response.* Boswellia extracts are clinically studied for supporting comfort and function in individuals with musculoskeletal discomfort.*[4,5]

• Dual Botanical Support: Together, curcumin and Boswellia support cytokine balance within normal limits, tissue comfort, and recovery capacity during times when the body is responding to increased detoxification or immune-related burden.*

Ideal for individuals undergoing detoxification or normal microbial turnover, who want targeted support for occasional discomfort, cytokine balance within normal limits, and metabolic buffering.* Useful for those seeking botanical support for whole-body comfort during periods of increased oxidative stress.*

• Clinically Studied Curcumin Delivery: Features Meriva® Turmeric Phytosome, a well-researched curcumin-phospholipid complex designed for enhanced curcuminoid absorption and tissue delivery.*

• Botanical Comfort Support*: Meriva® Turmeric Phytosome with standardized Boswellia serrata extract support musculoskeletal comfort, cytokine balance within normal limits, and recovery resilience.*

• Mineral Buffering Support*: Sodium and potassium bicarbonate support normal acid–base balance and electrolyte status during periods of increased metabolic demand.*

1. Cuomo J, Appendino G, Dern AS, Schneider E, McKinnon TP, Brown MJ, et al. Journal of Natural Products. 2011;74(4):664–9.
2. Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, et al. Alternative Medicine Review. 2010;15(4):337–44.
3. Drobnic F, Riera J, Appendino G, Togni S, Franceschi F, Valle X, et al. Journal of the International Society of Sports Nutrition. 2014;11:31.
4. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. BMC Complementary Medicine and Therapies. 2020;20:225.
5. Majeed M, Majeed S, Narayanan NK, Nagabhushanam K. BMC Complementary and Alternative Medicine. 2019;19:159.

Herxheimer Support combines mineral buffering with clinically relevant botanicals to support comfort, resilience, and balanced cytokine signaling within normal limits during periods of increased oxidative stress.*



FAQ

Q: What is changing with the CurcuWin product line?

A: We have updated the curcumin ingredient in this formula from CurcuWIN to Meriva® Turmeric Phytosome. As part of this change, the ingredient description on the label has also been updated to:

Meriva® Turmeric Phytosome (Curcuma longa extract (root) and sunflower phospholipid complex) (standardized to contain 18% curcuminoids)

You may also notice a natural color change in the encapsulated product. With the new ingredient, the powder inside the capsule may appear lighter and more orange in color rather than red. This color difference is expected and reflects the updated ingredient composition.



Q: Does this change affect the product’s quality or performance?

A: No. The product continues to meet established quality, strength, and uniformity specifications.



Q: Why is Meriva® more bioavailable than standard curcumin?

A: Standard curcumin is poorly absorbed due to low water solubility and rapid metabolism. Meriva® uses phytosome technology, which binds curcuminoids to phosphatidylcholine, helping them integrate with intestinal cell membranes and improving systemic availability.



Q: How does Meriva® compare to CurcuWIN?

A: Bioavailability: Both curcumin ingredients feature enhanced absorption mechanisms designed to overcome the poor bioavailability of standard curcumin extracts.

Science: Meriva® has a longer and broader clinical research history spanning joint health, physical function, antioxidant and cytokine balance, endothelial function and long-term tolerability with some studies spanning up to 18 months.

Focus: While CurcuWIN studies focus more heavily on high performance and short-term recovery, Meriva®’s long term clinical studies and demonstrated tolerability make it a good fit for longer-term support.