Buffered Vitamin C with Enhanced Immune Uptake and Antioxidant Support*
What It Does
Esterol Ester-C® provides highly bioavailable vitamin C as Ester-C® calcium ascorbate, a non-acidic, buffered form designed for optimal gastrointestinal tolerance and cellular uptake.* This formula supports immune resilience, antioxidant defenses, collagen formation, adrenal function, and connective tissue health.*
How It Works
• Ester-C® (calcium ascorbate, 1.35 g per 2 capsules): A unique, pH-neutral form of vitamin C with added metabolites that enhances uptake into white blood cells and prolongs retention for sustained biological activity.*[1-3]
• Bioflavonoids (quercetin, rutin, grape seed extract): Provide additional antioxidant activity, helping stabilize vitamin C while contributing vascular, immune, and connective tissue benefits.*[10,11]
• Buffered Formulation: Calcium ascorbate is gentler on the stomach and may reduce the risk of oxalate formation compared to ascorbic acid.*[8,9]
• Enhanced Immune Cell Activity: Clinical studies show Ester-C® supports improved neutrophil and NK cell function, histamine metabolism, and white blood cell activity compared to regular vitamin C.*[2,3,5]
• Adrenal and Connective Tissue Support: Vitamin C is concentrated in adrenal glands and plays a vital role in collagen synthesis and stress hormone production.*[6,7]
Who It’s For
Ideal for individuals seeking a well-tolerated, highly bioavailable form of vitamin C to support immune, antioxidant, and tissue health, especially those sensitive to acidic forms or with increased vitamin C needs.*
Special Features
This formula combines 1.35 grams of buffered vitamin C with complementary bioflavonoids to mirror nature’s delivery system, enhancing cellular uptake and tolerability. It is free from common allergens and formulated for clinical efficacy.*
References
1. Gruenwald J, et al. Adv Ther. 2006;23(1):171–178.
2. Calder PC, et al. Nutrients. 2025;17(2):279. doi:10.3390/nu17020279
3. Mitmesser SH, et al. Springerplus. 2016;5(1):1161. doi:10.1186/s40064-016-2605-7
4. Bush MJ, Verlangieri AJ. Res Commun Chem Pathol Pharmacol. 1987;57(1):137–140.
5. Verlangieri AJ, et al. Life Sci. 1991;48(23):2275–2281.
6. Dickerson B, et al. Nutrients. 2024;16(19):3358. doi:10.3390/nu16193358
7. Moyad MA, et al. Adv Ther. 2008;25(10):995–1009.
8. Van Straten M, Josling P. Adv Ther. 2002;19(3):151–159.
9. Moyad MA, et al. Urol Nurs. 2009;29(2):95–102.
10. Ganeshpurkar A, Saluja AK. Saudi Pharm J. 2017;25(2):149–164.
11. Deepika, Maurya PK. Molecules. 2022;27(8):2498. doi:10.3390/molecules27082498
