Advanced support for estrogen metabolism, hormone balance, and breast and cervical health with clinically studied BioResponse® DIM.*
What It Does
DIM Enhanced Hormone Detox promotes healthy estrogen metabolism and hormonal balance by supporting the production of beneficial 2-hydroxy estrogen metabolites.* This bioavailable formula may help maintain breast and cervical health, buffer testosterone-to-estrogen conversion, and optimize estrogen receptor signaling.*
How It Works
• Diindolylmethane (DIM): A metabolite of indole-3-carbinol from cruciferous vegetables that supports phase 1 estrogen detoxification by activating cytochrome P450 enzymes and enhancing the formation of 2-hydroxy estrogens.* [1-2]
• BioResponse® DIM Complex: A patented, microencapsulated form of DIM with enhanced bioavailability compared to crystalline DIM, promoting consistent absorption and clinical effectiveness.* [5-6]
• Histone Acetylase Inhibition: DIM also modulates estrogen receptor binding, providing additional support for hormone-sensitive tissue health.* [3,7]
• Testosterone-Estrogen Balance: DIM helps buffer excessive aromatization of testosterone into estrogen, supporting a healthy androgen-estrogen balance.* [8]
Who It’s For
Ideal for individuals seeking to optimize estrogen metabolism, support breast and cervical health, and promote hormonal balance, especially during times of hormonal transition or stress.*
Special Features
• Stable and Ready-to-Use: Unlike indole-3-carbinol (I3C), BioResponse® DIM is highly stable and does not require stomach conversion for activity.* [9]
• Clinically Studied and Bioavailable: DIM Enhanced Hormone Detox provides a form of DIM that has been extensively studied for its effectiveness in promoting beneficial estrogen metabolites and supporting overall hormone health.* [10]
DIM Enhanced Hormone Detox provides a clinically validated approach to promoting healthy estrogen metabolism, hormonal balance, and tissue-specific health through a highly bioavailable, stable DIM formulation.*
References
¹ Thomson CA, et al. Nutr Rev. 2016;74(7):432-43.
² Pondugula SR, et al. Toxicol Lett. 2015;232(3):580-9.
³ Tsuchiya Y, et al. Cancer Lett. 2005;227(2):115-24.
⁴ Thomson CA, et al. Nutr Rev. 2016;74(7):432-43.
⁵ Thomson CA, et al. Breast Cancer Res Treat. 2017;165(1):97-107.
⁶ Sepkovic DW, et al. Cancer Epidemiol Biomarkers Prev. 2009;18(11):2957-64.
⁷ Li Y, et al. Cancer Res. 2010;70(2):646-54.
⁸ Hwang C, et al. Am J Transl Res. 2016;8(1):166-76.
⁹ Anderton MJ, et al. Drug Metab Dispos. 2004;32(6):632-38.
¹⁰ Dalessandri KM, et al. Nutr Cancer. 2004;50(2):161-7.
