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Written by: Medical Affairs Team

Length: 3 minute read

Posted:

  • Metabolic Health

MTHFR: Why Genetic Testing Might Be Your Best Ally

Why Genetic Testing Might Be Your Best Ally

Laura Lewis, MS

In the realm of health and wellness, acronyms like MTHFR can seem like a secret code. Today we’re demystifying this puzzling abbreviation. We will shed light on why genetic testing for MTHFR mutations might just be the key to unlocking better health.  

The ABCs of MTHFR

Let’s start with the basics. MTHFR stands for methylenetetrahydrofolate reductase. The name is quite a mouthful. It refers to an enzyme that is crucial for processing folate in your body. Think of it as a molecular gatekeeper responsible for converting folate into its active form.  

The MTHFR gene codes for the MTHFR enzyme. When the MTHFR gene undergoes mutations, it can affect the enzyme’s efficiency. This can lead to a decreased ability to convert folate into l-methylfolate. The manifestations of these mutations are called gene variants. Variants have potential to wreak havoc on your health, manifesting in a myriad of ways, from mild to severe.  

The Puzzle Pieces: Signs of MTHFR Variants

Wondering if you might have an MTHFR variant? While the signs can vary widely and may overlap with other health issues, some common signs include:  

  • Fatigue that just won’t quit  
  • Mood swings or a chronically low mood  
  • Brain fog and memory issues  
  • Fertility struggles  
  • Ongoing physical discomfort in the body or head  

Why Genetic Testing Matters

Given the broad spectrum of ways in which MTHFR mutations present themselves, it’s easy to see why getting to the root cause is crucial. Enter genetic testing: a powerful tool that allows you to peek into your DNA. It can uncover any lurking mutations, including those in the MTHFR gene.  

By undergoing genetic testing, you’re not just playing detective; you’re arming yourself with valuable information that can guide personalized treatment and preventive strategies. Knowing whether you have an MTHFR variant empowers you to take proactive steps to optimize your health and potentially mitigate associated risks.  

Where to Go for Genetic Testing?

You can ask your trusted healthcare practitioner to conduct a genetic test for you, or you can choose a company you trust to conduct genetic testing for MTHFR.  

If you are considering genetic testing for MTHFR due to a long-term mood issue, specifically, results from these tests can also explain why certain products that help many others haven’t worked for you.   

The Bottom Line

In the grand tapestry of health, genetic testing for MTHFR mutations is but one thread, but it is an important one. By embracing the power of knowledge and taking proactive steps to support your body’s unique needs, you’re not just managing your health—you’re on the road to thriving.  

So, if you’ve been grappling with unexplained symptoms or suspect there might be more to your health story, consider embarking on the journey of genetic testing for MTHFR. It might just be the missing piece of the puzzle you’ve been searching for all along.  

 Disclaimer:
The information provided is for educational purposes only. Consult your physician or healthcare practitioner if you have specific questions before instituting any changes in your daily lifestyle including changes in diet, exercise, and supplement use.

Laura Lewis is a clinical researcher and science communicator with a Master of Science degree and a background in nutrition science and integrative health. She brings a decade of experience translating complex clinical data into accessible insights for healthcare practitioners and patients alike.

Laura has contributed to educational programming and strategic content development across the integrative and functional medicine space. Her strengths lie in evidence synthesis, practitioner engagement, and crafting communications that bridge the gap between scientific rigor and real-world application. At ARG, Laura supports clinical content development and educational initiatives that elevate practitioner confidence and product credibility.

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