• Artemisia annua: Provides artemisinin and other bioactives that support innate immune responses, cytokine balance, gut microbial ecology, and neuroprotective signaling.*[1–4]
• Houttuynia cordata: Contains quercetin, polysaccharides, and houttuynin that modulate immune signaling, support mucosal immunity, and influence microbiota composition.*[5]
• Uncaria tomentosa (Cat’s Claw): Delivers alkaloids and antioxidants that enhance white blood cell activity and strengthen endothelial barrier integrity, supporting innate immune defense.*[6–9]
• Coptis chinensis: A source of berberine and coptisine that support gut barrier health, microbial balance, and antioxidant activity, with added neuroprotective potential.*[10,11]
• Cordyceps sinensis: Supplies cordycepin and ergosterol to support immune function across tissues including brain, lung, and kidney via immunomodulatory pathways.*[12–14]
• Hericium erinaceus (Lion’s Mane): Enhances mucosal immunity by supporting secretory IgA and microbial balance, with additional effects on neuronal growth, mood, and sleep quality.*[15–17]
• Beta-glucan (1,3/1,6): A fungal-derived immunomodulator that activates macrophages and dendritic cells, enhances peptide production, and serves as a fermentable prebiotic for gut health.*[18,19]